{"product_id":"honokiol","title":"Honokiol","description":"\u003ch3\u003eHonokiol Magnolia Bark Extract Supplement\u003c\/h3\u003e\u003cp\u003eEach capsule contains \u003cstrong\u003eMagnolia officinalis Bark Extract (Honokiol) 100mg\u003c\/strong\u003e.\u003c\/p\u003e\u003ch4\u003ePhytochemistry\u003c\/h4\u003e\u003cp\u003eHonokiol belongs to the class of neolignin biphenols. As a polyphenol, it is relatively small, interacts with cell membrane proteins through intermolecular interactions, and is hydrophobic and readily dissolved in lipids.\u003c\/p\u003e\u003ch4\u003ePharmacological Actions\u003c\/h4\u003e\u003cp\u003eHonokiol readily crosses the blood-brain barrier, offering high bioavailability. Has antidepressant, anxiolytic, antioxidant, anti-HCV and anti-tumour effects.\u003c\/p\u003e\u003ch5\u003eEffect on CNS\u003c\/h5\u003e\u003cp\u003eExerts neuroprotective properties through multiple mechanisms including interaction with GABA receptors. Provides significant anti-stress benefit in moderately stressed adults, promotes neurite outgrowth and neurotrophic effects in cortical neurons. Shortens sleep latency and excites sleep-promoting neurons in the ventrolateral preoptic areas.\u003c\/p\u003e\u003ch5\u003eEffect on Tumour\u003c\/h5\u003e\u003cp\u003eHonokiol has shown pro-apoptotic effects in melanoma, sarcoma, leukaemia, prostate, bladder, lung, oral squamous cell carcinoma and colon cancer cell lines.\u003c\/p\u003e\u003ch4\u003eBenefits\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eReduce anxiety and enhance sleep\u003c\/li\u003e\n\u003cli\u003eSupportive treatment for cancers\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eDosage\u003c\/h4\u003e\u003cp\u003eAdult — one to two capsules two times daily after meal\u003c\/p\u003e\u003ch4\u003eDrug Interactions\u003c\/h4\u003e\u003cp\u003eMay interact with paracetamol, benzodiazepines (additive effect), antiplatelet medications (additive effect). May stimulate corticosterone secretion or increase steroid medication concentrations. May cause sleepiness, drowsiness, vertigo and dizziness in patients taking muscle relaxants.\u003c\/p\u003e\u003ch4\u003eContraindications\u003c\/h4\u003e\u003cp\u003eRenal insufficiency, pregnancy and lactation\u003c\/p\u003e\u003ch4\u003eSide Effects\u003c\/h4\u003e\u003cp\u003eHeartburn, shaking hands, perilabial numbness in some individuals.\u003c\/p\u003e\u003ch4\u003eQuantity Supplied\u003c\/h4\u003e\u003cp\u003e60 capsules per bottle\u003c\/p\u003e","brand":"Fame Pharma","offers":[{"title":"Default Title","offer_id":45926822150188,"sku":null,"price":30002000.0,"currency_code":"MMK","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0736\/2042\/2700\/files\/image_2c8a9b52-4189-4c85-a06a-98fd7fe02581.png?v=1785936618","url":"https:\/\/ascendshopping.com\/my\/products\/honokiol","provider":"ascendshopping","version":"1.0","type":"link"}