JavaHerb®

JavaHerb® Java Tea (Orthosiphon aristatus) Supplement

Each tablet contains Orthosiphon aristatus (Java Tea) Leaf Extract 250mg.

Active Constituents

Active principles for controlling blood sugar are diterpenes — isopimarine-type (orthosiphones A & B, orthosiphols A, B, F, G, H & I) and pimarine-type (neoorthosiphols A & B). Also contains saponins, alkaloids, tannin, essential oil, flavonoids (sinensetin, tetramethoxy flavones, trimethylapigenin, tetramethylluteolin), choline, betaine, organic acids (tartaric, citric, glycolic) and potassium salts.

Pharmacological Actions

1. Hypoglycaemic Effect

Oral administration of aqueous extract of O. aristatus (1g/kg) produces a significant decrease in blood glucose concentration in normoglycaemic rats.

2. Diuretic Effect

Diuretic effect is partially due to potassium content and flavones sinensetin and 3’-hydroxy-5,6,7,4’-tetramethoxyflavone. Methylripariochromene A (100mg/kg) increases urinary volume after oral administration.

3. Antihypertensive Effect

Methylripariochromene A produces continuous reduction in systolic blood pressure and decreased heart rate in hypertensive rats. Also suppresses agonist-induced contractions in the aorta and decreases contractile force in isolated guinea pig atria.

Indication

Type II Diabetes mellitus

Dosage

Adult — one to two tablets two times daily, half an hour before meal

Contraindications

Pregnancy and lactation

Side Effects

Well tolerated in recommended dose.

Quantity Supplied

60 tablets per bottle