{"product_id":"mangosteen","title":"Mangosteen","description":"\u003ch3\u003eMangosteen Garcinia mangostana Xanthone Supplement\u003c\/h3\u003e\u003cp\u003eEach tablet contains \u003cstrong\u003eGarcinia mangostana Pericarp Extract (Xanthones) 200mg\u003c\/strong\u003e.\u003c\/p\u003e\u003ch4\u003ePhytochemistry\u003c\/h4\u003e\u003cp\u003eApproximately 40 of over 200 naturally occurring xanthones are found in Garcinia mangostana. Most studied xanthones: α-, β- and γ-mangostins, garcinone E, 8-deoxygartanin and gartanin. They possess antioxidant, anti-tumoral, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal and anti-viral properties.\u003c\/p\u003e\u003ch4\u003ePharmacological Actions\u003c\/h4\u003e\u003ch5\u003eAnti-microbial Activities\u003c\/h5\u003e\u003cp\u003eBroad spectrum anti-bacterial activity against Gram-positive and Gram-negative bacteria including S. aureus, P. aeruginosa, S. typhimurium and B. subtilis. Active against both methicillin-resistant and methicillin-sensitive S. aureus. α- and β-mangostin and garcinone B exhibit potent inhibitory effect against Mycobacterium tuberculosis (MIC 6.25 µg\/ml).\u003c\/p\u003e\u003ch5\u003eAnti-allergic Action\u003c\/h5\u003e\u003cp\u003eα- and γ-mangostin are histaminergic and serotonergic receptor blocking agents respectively. Mangosteen fruit extract strongly inhibits histamine release and prostaglandin E2 synthesis.\u003c\/p\u003e\u003ch5\u003eAnti-inflammatory Action\u003c\/h5\u003e\u003cp\u003eα-mangostin attenuates inflammatory mediators TNF-α and IL-6. Garcinone B interferes with NF-κB activation. γ-mangostin inhibits COX-1 and COX-2 activities and conversion of arachidonic acid to PGE2. Mangosteen juice ingestion decreases serum C-reactive protein levels.\u003c\/p\u003e\u003ch5\u003eAnti-tumour Activities\u003c\/h5\u003e\u003cp\u003eXanthones cause cell cycle arrest, suppress tumour cell proliferation, induce apoptosis and differentiation, reduce inflammation and inhibit adhesion, invasion and metastasis. At low doses, tumour growth is delayed; at high doses, tumour size gradually decreases with complete regressions observed.\u003c\/p\u003e\u003ch4\u003eBenefits\u003c\/h4\u003e\u003cul\u003e\n\u003cli\u003eNatural antibiotics\u003c\/li\u003e\n\u003cli\u003eEase allergic responses\u003c\/li\u003e\n\u003cli\u003eReduce inflammation\u003c\/li\u003e\n\u003cli\u003eSuppress abnormal cell growth\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch4\u003eDosage\u003c\/h4\u003e\u003cp\u003e12 years and above — one tablet two times daily after meal\u003c\/p\u003e\u003ch4\u003eCombination Therapy\u003c\/h4\u003e\u003cp\u003eCan be used in combination with other chemotherapeutic agents as adjuvant therapy to achieve increased therapeutic efficacy and minimize chemotherapy-induced toxicity.\u003c\/p\u003e\u003ch4\u003eSide Effects\u003c\/h4\u003e\u003cp\u003eIrritation of gastric mucosa and constipation may occur in some individuals.\u003c\/p\u003e\u003ch4\u003eQuantity Supplied\u003c\/h4\u003e\u003cp\u003e60 tablets per bottle\u003c\/p\u003e","brand":"Fame Pharma","offers":[{"title":"Default Title","offer_id":45927981088812,"sku":null,"price":24000.0,"currency_code":"MMK","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0736\/2042\/2700\/files\/mangosteen.png?v=1785950399","url":"https:\/\/ascendshopping.com\/my\/products\/mangosteen","provider":"ascendshopping","version":"1.0","type":"link"}